UF researchers identify key target for cancer therapies

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Omschrijving
New therapies must target a key protein interaction to destroy aggressive cancer cells’ protective force field, University of Florida scientists reported this week at the American Association for Cancer Research’s annual meeting in San Diego. The barrier deflects damage from radiation or chemotherapy, making some cancer cells difficult to destroy, but researchers from UF and the University of North Carolina at Chapel Hill may have discovered why. Their study revealed that mutations in the tumor-suppressing p53 protein lead to overabundance of a second protein called focal adhesion kinase, or FAK, which makes the cells less vulnerable to attack.

 

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