The Potential Effect of Statins on Rituximab Immunotherapy
Omschrijving
Assuming long-term statin treatment does indeed substantially reduce CD20 detection in vivo, two obvious changes to clinical management should be made. First, extensive use of statins for the treatment of hypercholesterolemia should be a contraindication for the use of CD20 as a diagnostic marker for mature B cells. Second, statins should be removed from the treatment of patients with either malignant or autoimmune disease who are required to undergo CD20-specific therapy.
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Categorie: statines - kanker - artritis - lupus
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